Regular paperDirect glycosylation of protected O-tritylserine esters and oligopeptides

Add time:08/21/2019    Source:sciencedirect.com

N-Fmoc-3-O-Tr-l-serine methyl and benzyl esters, as well as a tripeptide FmocAlaSer(Tr)GlyOBn were directly glycosylated by 3,4,6-tri-O-acetyl-1,2-O-(1-cyanoethylidene)-α-d-galactopyranose in the presence of TrClO4 in dichloromethane, yielding 32–57% of N-Fmoc-3-O-(2,3,4,6-tetra-O-acetyl-β-d-galactopyranosyl)-l-serine esters and the corresponding tripeptide.

We also recommend Trading Suppliers and Manufacturers of O-BENZYL-L-SERINE METHYL ESTER HYDROCHLORIDE (cas 19525-87-2). Pls Click Website Link as below: cas 19525-87-2 suppliers

Prev:Single-crystal and molecular structures of six hydrogen-bonding 3D supramolecular salts from 2-aminobenzoic acid, 3-aminobenzoic acid, 4-aminobenzoic acid, and acidic components
Next:Synthesis and antiproliferative activity of new bioconjugates of Salinomycin with amino acid esters)