Synthesis and antiproliferative activity of new bioconjugates of Salinomycin with amino acid esters
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Add time:08/22/2019 Source:sciencedirect.com
New Salinomycin (SAL) bioconjugates with amino acid methyl esters were obtained and their antiproliferative activity against cancer cell lines including drug-resistant ones was studied. New compounds exhibit antiproliferative activity towards leukemia and doxorubicin-resistant colon adenocarcinoma cell line and are more effective and less toxic than the commonly currently used anticancer drugs.
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