Structure and antimycobacterial activity of the novel organometallic [Pd(C-bzan)(SCN)(Dppp (cas 110954-36-4))] compound

Add time:08/27/2019    Source:sciencedirect.com

The organometallic compound [Pd(C-bzan)(SCN)(dppp)] {bzan = N-benzylideneaniline, dppp = 1,3-bis(diphenylphosphino)propane} was synthesized and characterized by elemental analyses, infrared and 1H and 31P{1H} NMR spectroscopies. The crystal and molecular structures of the title complex were determined by single-crystal X-ray diffraction techniques. In vitro antimycobacterial evaluation demonstrated that the compound [Pd(C-bzan)(SCN)(dppp)] displayed a MIC of 5.15 μM, which is superior than those values found for some commonly used anti-TB drugs and other Pd(II) complexes.

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