New approach to 4-phenyl-β-aminotetralin from 4-(3-halophenyl)tetralen-2-ol phenylacetate
-
Add time:08/29/2019 Source:sciencedirect.com
Mixed trifluoroacetyl phenylacetyl anhydride and 3-halostyrenes (fluoro, chloro, and bromo) or vinylcycloalkanes (cyclohexyl and cyclooctyl), undergo cascade Friedel–Crafts cycli-acylalkylation, enolization, and O-acylation to give 4-substituted tetralen-2-ol phenylacetates, without additional solvent in good yields. Base alcoholysis of 4-phenyltetralen-2-ol phenylacetate reveals the tetral-2-one for asymmetric transfer hydrogenation. Bromophenyltetralen-2-ol phenylacetate undergoes Suzuki coupling, and provides a short route to trans-4-phenyl-β-aminotetralin.
We also recommend Trading Suppliers and Manufacturers of Sodium phenylacetate (cas 114-70-5). Pls Click Website Link as below: cas 114-70-5 suppliers
Prev:Conformational analysis and electronic interactions of some 2-ethylsulfinyl-(4′-substituted)-phenylacetates
Next:Evaluation of physically small p-phenylacetate-modified carbon electrodes against fouling during dopamine detection in vivo) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Dual investigation of lanthanide complexes with cinnamate and phenylacetate ligands: Study of the cytotoxic properties and the catalytic oxidation of styrene08/31/2019
- Evaluation of physically small p-phenylacetate-modified carbon electrodes against fouling during dopamine detection in vivo08/30/2019
- Conformational analysis and electronic interactions of some 2-ethylsulfinyl-(4′-substituted)-phenylacetates08/28/2019
- Regular ArticleSuppression of tumourigenicity, and induction of differentiation of the canine mammary tumour cell line MCM -B2 by Sodium phenylacetate (cas 114-70-5)08/27/2019
- In vitro differentiation of human neuroblastoma cells induced by Sodium phenylacetate (cas 114-70-5)08/26/2019
- Regular ArticleExpression of Transcription Factors During Sodium phenylacetate (cas 114-70-5) Induced Erythroid Differentiation in K562 Cells☆08/25/2019
- Spectroscopic and theoretical study on alkali metal phenylacetates08/24/2019
- Radiopotentiation of human brain tumor cells by Sodium phenylacetate (cas 114-70-5)08/23/2019
- Pharmacokinetics of Sodium phenylacetate (cas 114-70-5) and sodium benzoate following intravenous administration as both a bolus and continuous infusion to healthy adult volunteers08/22/2019
-
Health and Chemical more >
-
Related Products
- Sodium 2,4-dimethylbenzenesulfonate
- SODIUM γ-FLUORO-β-HYDROXYBUTYRATE
- Sodium ((3-methoxy-1-methyl-3-oxo-1-propenyl)amino)phenylacetate
- Sodium (+)-10-camphorsulfonate
- Sodium (2-carbamoylphenoxy)acetate
- Sodium (2-methyl-4-chlorophenoxy)acetate
- Sodium (6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate pentahydrate
- Sodium (C10-16)alkylbenzenesulfonate
- Sodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)propyl)-1,3-benzodioxole-2,2-
- Sodium (S)-lactate