A new synthetic approach to 2,3-dideoxy-2-fluoro-β-d-threo-pentofuranose, the fluorofuranose unit of the anti-HIV-active nucleoside, β-FddA
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Add time:08/27/2019 Source:sciencedirect.com
The fluorinated furanose unit of the anti-HIV-active nucleoside (2,3-dideoxy-2-fluoro-β-d-threo-pentofuranosyl)adenine, β-FddA, has been synthesized as its 5-trityl derivative with high stereocontrol from (S)-trityl glycidol and phenylthioacetic acid.
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