TBAI/TBHP mediated oxidative cross coupling of ketones with phenols and carboxylic acids: Direct access to benzofurans

Add time:08/24/2019    Source:sciencedirect.com

TBAI/TBHP mediated oxidative cross coupling of phenols and carboxylic acids with ketones has been reported under metal-free, base free, solvent free conditions enabling environmentally benign synthesis of aryloxyketones, acyloxy ketones and benzofurans. Phenoxyketones and acyloxylcarbonyl compounds were synthesized in good to high yields, where as benzofurans were synthesized in moderate yields. This method is operationally simple, works under mild conditions, using commercially available as well as inexpensive TBAI and an oxidant TBHP.

We also recommend Trading Suppliers and Manufacturers of 3-BROMO-4-HYDROXY-5-METHOXY-BENZOIC ACID METHYL ESTER (cas 108249-43-0). Pls Click Website Link as below: cas 108249-43-0 suppliers

Prev:Original ArticleSynthesis and biological evaluation of 2-(phenyl)-3H-benzo[d]imidazole-5-carboxylic acids and its methyl esters as potent anti-breast cancer agents
Next:Heterolignanolides. Furo- and thieno-analogues of podophyllotoxin and thuriferic acid)