Effect of thiram and dithiocarbamate pesticides on the gastrointestinal absorption and distribution of nickel in mice

Add time:08/23/2019    Source:sciencedirect.com

Oral administration of dimethyldithiocarbamate pesticides (ferbam, ziram or sodium dimethyldithiocarbamate) or thiram together with nickel resulted in increased levels of the metal in several tissues of rats, in comparison with animals given only nickel. In contrast, the administration of nickel together with ethylene- or propylenebisdithiocarbamates (zineb, maneb, nabam or propineb) resulted in unchanged tissue levels or, most marked for nabam, reduced the tissue concentrations of the metal. Among the compounds which were able to increase tissue levels of nickel, thiram was the most effective one, followed in decreasing order by ferbam, ziram and sodium dimethyldithiocarbamate. The central nervous system was among the tissues which showed the highest relative increase. For thiram, an accumulation of nickel was observed in the pancreatic islets. The results are discussed in relation to the formation of chelates between nickel and the studied compounds or their metabolites.

We also recommend Trading Suppliers and Manufacturers of Nickel bis(dimethyldithiocarbamate) (cas 15521-65-0). Pls Click Website Link as below: cas 15521-65-0 suppliers

Prev:Research articlesEnhanced magnetic properties of highly crystalline cobalt ferrite fibers and their application as gas sensors
Next:Comparative investigation of N,N′-bis-(dithiocarboxy)piperazine and diethyldithiocarbamate as precipitants for Ni(II) in simulated wastewater)