Chapter 2 - 1-Substituted Piperidines

Add time:08/25/2019    Source:sciencedirect.com

This chapter describes methods of synthesis, pharmacological properties, and the use of derivatives of 1-phenyl-3-(piperidin-1-yl)propan- and butan-1-ol, such as trihexyphenidyl, biperiden, pridinol, cycrimine, and diphenidol, and pirmenol; derivatives of 2-(piperidin-1-yl)ethan-1-ol or 3-(piperidin-1-yl)propan-1-ols cloperastine, benproperine, pipazetate, and raloxifene; derivatives of 3-(piperidin-1-yl)propane-1,2-diol—diperodon and 3-(piperidin-1-yl)propane-1,1-diol—pipoxolan; derivative of 1-phenyl 3-(piperidin-1-yl)propan-1-one—dyclonine; and the derivative of 2,2-diphenyl-4-(piperidin-1-yl)butanamide—fenpiverinium bromide.

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