One pot, simple, and efficient synthesis of (E)- and (Z)-3-allylidene-β-lactams from 3-allyl-3-phenylseleno-β-lactams: analogues of β-lactamase inhibitors
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Add time:08/30/2019 Source:sciencedirect.com
The direct synthesis of (E)- and (Z)-3-allylidene-β-lactams from 3-allyl-3-phenylseleno-β-lactams under mild conditions has been described. 3-Allyl-3-phenylseleno-β-lactams acts as an efficient substrate for in situ oxidation and elimination in one step. This method is simple, convenient, fast, and very efficient.
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