Original articleAntioxidant, antimicrobial and cytotoxic activities of gold nanoparticles capped with Quercetin (cas 117-39-5)
-
Add time:08/28/2019 Source:sciencedirect.com
In the present work, we report the antioxidant, antimicrobial and cytotoxic activities of quercetin-capped gold nanoparticles (AuNPsQct). The synthesis of AuNPsQct was confirmed by UV–Vis spectroscopy, FTIR and transmission electron microscopy (TEM) analyses. The FTIR spectrum showed the integrity of the quercetin molecules on the nanoparticle surface. The TEM images showed sizes less than 100 nm and a slight spherical shape. The electrostatic stability was confirmed by the zeta potential method. The antioxidant activity of quercetin, evaluated by DPPH, ABTS and nitric oxide free radical scavenging methods, was preserved in the gold nanoparticles, furthermore quercetin-capped gold nanoparticles (IR50 0.37 µg/mL) demonstrated a higher antioxidant activity than free quercetin (IR50 0.57 µg/mL) by nitric oxide free radical scavenging method. Strong antifungal activity was observed for Aspergillus fumigatus with concentrations ranging from 0.1 to 0.5 mg/mL. The nanoparticles with quercetin did not exhibit cytotoxicity to human fibroblasts (L929 cells). In conclusion, these results suggest that AuNPsQct, produced by cost-effective method, can act as a promising candidate for different medical applications.
We also recommend Trading Suppliers and Manufacturers of Quercetin (cas 117-39-5). Pls Click Website Link as below: cas 117-39-5 suppliers
Prev:Research ArticleIn vitro bioaccessibility and bioavailability of Quercetin (cas 117-39-5) from the Quercetin (cas 117-39-5)-fortified bread products with reduced glycemic potential
Next:Quercetin (cas 117-39-5) inhibited mesangial cell proliferation of early diabetic nephropathy through the Hippo pathway) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Quercetin (cas 117-39-5) suppressed NADPH oxidase-derived oxidative stress via heme oxygenase-1 induction in macrophages09/04/2019
- Antioxidant activity of Quercetin (cas 117-39-5) in Eudragit-coated liposomes for intestinal delivery09/03/2019
- Quercetin (cas 117-39-5) based derivatives as sirtuin inhibitors09/02/2019
- In silico and in vitro approach of Allium cepa and isolated Quercetin (cas 117-39-5) against MDR bacterial strains and Mycobacterium smegmatis09/01/2019
- Quercetin (cas 117-39-5) glycosides prevent dexamethasone-induced muscle atrophy in mice08/31/2019
- Supercritical CO2 impregnation of silica microparticles with Quercetin (cas 117-39-5)08/30/2019
- Quercetin (cas 117-39-5) inhibited mesangial cell proliferation of early diabetic nephropathy through the Hippo pathway08/29/2019
- Research ArticleIn vitro bioaccessibility and bioavailability of Quercetin (cas 117-39-5) from the Quercetin (cas 117-39-5)-fortified bread products with reduced glycemic potential08/27/2019
- Original articleRedox properties of individual Quercetin (cas 117-39-5) moieties08/26/2019