Shock/Sepsis/Trauma/Critical CareRADICICOL (cas 12772-57-5), an Hsp90 inhibitor, inhibits intestinal inflammation and leakage in abdominal sepsis
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Add time:09/03/2019 Source:sciencedirect.com
BackgroundIntestinal injury is a key feature in sepsis. Inhibitors of heat shock protein 90 (Hsp90) have been shown to exert protective effects in models of inflammation. Herein, we hypothesized that Hsp90 might regulate intestinal inflammation and leakage in abdominal sepsis.
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