ExperimentalMECHANISMS OF HALOTHANE ADSORPTION BY DRY SODA-LIME

Add time:08/30/2019    Source:sciencedirect.com

Using fresh soda-lime (15% water by weight) the soda lime/air partition coefficient of halothane was found to decrease as a function of vapour phase halothane concentration from 2 40 at 0.3% halothane by volume to 1.15 at 2.6%, but adsorption generally followed Henry’s law. However, soda-lime dried to a constant weight and subsequently exposed to various concentranons of halothane adsorbed approximately 320 μlitre of vaporized liquid halothane per 100 g before a measurable concentration of halothane was detected in the vapour phase. Adding additional halothane then caused a linear increase in vapour concentration. We conclude that dry soda-lime can adsorb large quantities of halothane by a mechanism which is nimilar to that of a molecular sieve. After these “high affinity” sites are satisfied, additional halothane is adsorbed by a mechanism following Henry’s law.

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