The synthesis of functionalised β- and γ-lactams by cyclisation of enamides using copper(I) or ruthenium(II)
-
Add time:08/29/2019 Source:sciencedirect.com
Cyclisation of a variety of halo-enamides with copper(I) or ruthenium(II) complexes has been investigated. The regioselectivity of the radical cyclisation, which can proceed via either a 4-exo or 5-endo pathway, to form β- or γ-lactam products respectively, is determined by the nature of the metal oxidant and the reaction conditions. Thus, whereas copper(I)/bipyridine reactions give predominantly γ-lactams, the use of copper(I)/TMEDA or dichlorotris(triphenylphosphine)ruthenium(II) affords mainly β-lactams.
We also recommend Trading Suppliers and Manufacturers of DICHLOROTRIS(TRIPHENYLPHOSPHINE)RUTHENIUM(II) (cas 15555-77-8). Pls Click Website Link as below: cas 15555-77-8 suppliers
Prev:The kinetics and mechanism of homogeneous hydrogen transfer from alcohols to benzylideneacetone catalyzed by dichlorotris(triphenylphosphine)ruthenium(II)
Next:Metathesis of methyl soyate with ruthenium catalysts) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- NoteSynthesis, characterization, and catalytic behaviour of a dimeric ruthenium(II) methoxydiphenylphosphane complex09/03/2019
- Mechanistic investigation of homogeneous hydrogen transfer from 1-phenylethanol to cyclohexanone catalyzed by dichlorotris(triphenylphosphine)- ruthenium(II)09/02/2019
- The mechanism of the addition of haloalkanes to alkenes in the presence of dichlorotris(triphenylphosphine)ruthenium(II), [RuCl2(PPh3)3]09/01/2019
- Dichlorotris(triphenylphosphine)ruthenium(II) catalyzed dehydrogenation of some natural products using cyclohexanone as acceptor08/31/2019
- Metathesis of methyl soyate with ruthenium catalysts08/30/2019
- The kinetics and mechanism of homogeneous hydrogen transfer from alcohols to benzylideneacetone catalyzed by dichlorotris(triphenylphosphine)ruthenium(II)08/28/2019
- Hydrogenation and transfer hydrogenation of d-fructose catalyzed by dichlorotris (triphenylphosphine) ruthenium (II)08/27/2019
