Percutaneous absorption of 2-amino-4-nitrophenol in the rat
-
Add time:09/02/2019 Source:sciencedirect.com
The absorption of 14C-labelled 2-amino-4-nitrophenol (ANP) in two hair dyeing formulations was investigated after application to the skin of rats. After 1 and 5 days, 0.21 and 0.36%, respectively, of the administered radioactivity was absorbed from formulation 1 which contained carboxymethylcellulose as a thickening agent. Absorption was greater (1.12% after 1 day, 1.67% after 5 days) from formulation 2 which contained oleic acid and isopropanol. Complementary studies of absorption after administration of [14C]ANP by sc injection or oral gavage were also carried out. The radioactivity was rapidly excreted, predominantly in the urine, in both cases. Biliary excretion was also detected in an oral study.
We also recommend Trading Suppliers and Manufacturers of 4-Amino-2-nitrophenol (cas 119-34-6). Pls Click Website Link as below: cas 119-34-6 suppliers
Prev:Plasma levels and kinetic disposition of 2,4-dinitrophenol and its metabolites 2-amino-4-nitrophenol and 4-Amino-2-nitrophenol (cas 119-34-6) in the mouse
Next:CommunicationPalladium nanoflowers supported on amino-fullerene as novel catalyst for reduction of 4-nitrophenol) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Feed-back action of nitrite in the oxidation of nitrophenols by bicarbonate-activated peroxide system09/04/2019
- CommunicationPalladium nanoflowers supported on amino-fullerene as novel catalyst for reduction of 4-nitrophenol09/03/2019
- Plasma levels and kinetic disposition of 2,4-dinitrophenol and its metabolites 2-amino-4-nitrophenol and 4-Amino-2-nitrophenol (cas 119-34-6) in the mouse09/01/2019
- Second- and third-order nonlinear optical and quantum chemical studies on 2-amino-4-picolinium-nitrophenolate-nitrophenol: A phasematchable organic single crystal08/31/2019
- Preparation of magnetic imprinted polymer particles via microwave heating initiated polymerization for selective enrichment of 2-amino-4-nitrophenol from aqueous solution08/30/2019
- Spectrophotometric study on the proton transfer reaction between 2-amino-4-methylpyridine with 2,6-dichloro-4-nitrophenol in methanol, acetonitrile and the binary mixture 50% methanol + 50% acetonitrile08/29/2019
- Synthesis, crystal growth, structure and characterization of a novel third order nonlinear optical organic single crystal: 2-Amino 4,6-Dimethyl Pyrimidine 4-nitrophenol08/28/2019
