β-Hydroxylation of N-acetyl-3,4-Dimethoxyphenethylamine (cas 120-20-7) and the influence of iproniazid on the demethylation of this compound in vivo in the rat

Add time:08/30/2019    Source:sciencedirect.com

N-acetyl-β-hydroxy-3,4-dimethoxyphenethylamine was found in the urine of rats after intraperitoneal administration of either 3,4-dimethoxyphenethylamine or N-acetyl-3,4-dimethoxyphenethylamine. Identification was made from Chromatographic, cocrystallization and mass spectral data. The monoamine oxidase inhibitor, iproniazid, was found to diminish the extent of demethylation of N-acetyl-3,4-dimethoxyphenethylaminein vivo by 17 per cent.

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