Kinetic resolution of phenyl methyl SULFOXIDE (cas 120-62-7)s by mammalian methionine SULFOXIDE (cas 120-62-7) reductase A

Add time:08/31/2019    Source:sciencedirect.com

Chiral SULFOXIDE (cas 120-62-7)s are widely used in organic synthesis as chiral auxiliaries. There are numerous strategies for the preparation of enantiomerically pure sulfoxides, based either on the enantioselective oxidation of sulphides or the enantiospecific reduction of sulfoxides. For both cases, bioconversion techniques have been developed and proposed for large-scale synthesis. Methionine sulfoxide reductase enzymes (MsrA and MsrB) catalyse the stereoselective conversion of methionine sulfoxide to methionine. MsrA can also catalyse the reduction of other exogenous sulfoxides, including p-tolyl methyl sulfoxide. However, the stereoselectivity towards this type of substrate is not yet well characterized. The activity and enantioselectivity of MsrA toward several aryl methyl sulfoxides is presented in this paper.

We also recommend Trading Suppliers and Manufacturers of SULFOXIDE (cas 120-62-7). Pls Click Website Link as below: cas 120-62-7 suppliers

Prev:ReviewGenetic regulation of longevity and age-associated diseases through the methionine SULFOXIDE (cas 120-62-7) reductase system☆☆☆
Next:Electrochemical mineralization of dimethyl SULFOXIDE (cas 120-62-7) on boron-doped diamond electrodes)