Thermal stability of mafenide and amphotericin B topical solution

Add time:08/29/2019    Source:sciencedirect.com

ObjectiveFungal infections remain a major cause of mortality in the burned population. Mafenide acetate/amphotericin B solution (SMAT) has been used topically for prophylaxis and treatment of these infections. Current manufacturer guidelines only guarantee the stability of mafenide solution and amphotericin B at room temperature. Additionally, the recommended maximum storage time for mafenide solution is 48 h, leading to significant financial and material loss when unused solutions are discarded. The purpose of this study was to characterize the chemical stability, structure and bioactivity of SMAT stored at 2 °C, 25 °C, and 40 °C for up to 90 days.

We also recommend Trading Suppliers and Manufacturers of Mafenide acetate (cas 13009-99-9). Pls Click Website Link as below: cas 13009-99-9 suppliers

Prev:Skin wound healing acceleration by Ag nanoparticles embedded in PVA/PVP/Pectin/Mafenide acetate (cas 13009-99-9) composite nanofibers
Next:Original contributionComparison between topical honey and Mafenide acetate (cas 13009-99-9) in treatment of auricular burn)