Polyethylenimine attached-poly(3-chloro-2-hydroxypropyl methacrylate-co-ethylene dimethacrylate) monosized-porous microspheres as a new separation medium for polar compounds

Add time:07/15/2019    Source:sciencedirect.com

Monosized-porous and hydrophilic polymer microspheres with reactive chlorine functionality were first obtained in the form of poly(3-chloro-2-hydroxypropyl methacrylate-co-ethylene dimethacrylate), poly(HPMA-Cl-co-EDMA) copolymer by a new seeded polymerization. A macromolecular ligand, polyethylenimine (PEI) was covalently attached onto the poly(HPMA-Cl-co-EDMA) microspheres via a single stage reaction between 3-chloro-2-hydroxypropyl and amine groups. PEI attached-poly(HPMA-Cl-co-EDMA) microspheres were slurry packed into the microbore columns and used as stationary phase in hydrophilic interaction chromatography (HILIC) mode. The separation of various compounds, nucleosides, polar organics and peptides was successfully performed. The results showed that hydrophilic poly(HPMA-Cl-co-EDMA) microspheres are a new, alternative starting material for the synthesis of stationary media with different functionalities for various liquid chromatographic applications.

We also recommend Trading Suppliers and Manufacturers of 2-CHLORO-3-(3-CHLOROPROPYL)-7-METHOXYQUINOLINE (cas 159383-58-1). Pls Click Website Link as below: cas 159383-58-1 suppliers

Prev:The immobilization of 3-(chloropropyl)triethoxysilane onto silica by a simple one-pot synthesis
Next:Miscibility of poly(3-chloropropyl methacrylate) with various polymethacrylates)