Synthesis of alkylphosphon(othio)ate analogues of DNA
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Add time:08/30/2019 Source:sciencedirect.com
Easily accessible bis(diisopropylamino)alkylphosphines (alkyl is methyl, n-butyl or n-octyl) are convenient reagents for the synthesis of DNA fragments having an alkylphosphonate or alkylphosphonothioate linkage at a predetermined site in solution and on solid support.
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