Structure Elucidation and Chemistry of Catharanthus Alkaloids III: Structure of LEUROSINE (cas 23360-92-1), an Active Anticancer Alkaloid

Add time:07/16/2019    Source:sciencedirect.com

Evidence for the structure of the antitumor alkaloid leurosine is presented, together with the explanations for the mass spectral fragmentation patterns observed. Nuclear magnetic resonance spectroscopic data support the proposal that leurosine contains an epoxide moiety, and is closely related to the other Catharanthus antitumor alkaloids vincaleukoblastine and leurosidine.

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