Novel approach to the synthesis of aliphatic and aromatic α-keto acids
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Add time:08/31/2019 Source:sciencedirect.com
A new practical and efficient synthesis of α-keto acids was accomplished starting from the synthon 1,4-diacetylpiperazine-2,5-dione. The synthesis encompasses both aromatic and aliphatic substrates proving to be versatile and innovative with excellent carbon economy and recycling of the glycine by-product.
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