Intraerythrocytic stages of Plasmodium falciparum biosynthesize vitamin E
-
Add time:08/30/2019 Source:sciencedirect.com
The 2-C-methyl-d-erythritol-4-phosphate and shikimate pathways were found to be active in Plasmodium falciparum and both can result in vitamin E biosynthesis in plants and algae. This study biochemically confirmed vitamin E biosynthesis in the malaria parasite, which can be inhibited by usnic acid. Furthermore, we found evidence pointing to a role of this vitamin in infected erythrocytes. These findings not only contribute to current understanding of P. falciparum biology but also reveal a pathway that could serve as a chemotherapeutic target.
We also recommend Trading Suppliers and Manufacturers of vitamin K1-hydroperoxide (cas 15576-39-3). Pls Click Website Link as below: cas 15576-39-3 suppliers
Prev:Vitamin K: Redox-modulation, prevention of mitochondrial dysfunction and anticancer effect
Next:Inhibition of diabetic-cataract by vitamin K1 involves modulation of hyperglycemia-induced alterations to lens calcium homeostasis) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Review ArticleVitamins C and E: Beneficial effects from a mechanistic perspective09/04/2019
- Modeling the impact of residual fat-soluble vitamin (FSV) contents on the oxidative stability of commercially refined vegetable oils09/03/2019
- ω-Hydroxylation of α-tocopheryl quinone reveals a dual function for cytochrome P450-4F2 in vitamin E metabolism09/02/2019
- Chapter 9 - Fat-Soluble Vitamins and Nonnutrients09/01/2019
- Inhibition of diabetic-cataract by vitamin K1 involves modulation of hyperglycemia-induced alterations to lens calcium homeostasis08/31/2019
- Vitamin K: Redox-modulation, prevention of mitochondrial dysfunction and anticancer effect08/29/2019
-
Health and Chemical more >