Investigation of the interaction of hydroxyapatite with technetium in association with Stannous pyrophosphate (cas 15578-26-4)
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Add time:08/30/2019 Source:sciencedirect.com
The individual components of technetium-99m stannous pyrophosphate are studied with respect to their interaction with hydroxyapatite. It is demonstrated that the role of the pyrophosphate molecule is one of a solubilizing and transporting molecule to carry the technetium atom to the site of the hydroxyapatite where the chelate disassociates and both the pyrophosphate and the technetium individually bind to the hydroxyapatite. The stannous ion is shown to associate with the hydroxyapatite also and although also solubilized by the pyrophosphate appears to be less strongly associated with the pyrophosphate.
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