Original ArticleDevelopment and characterization of ethylcellulose based microsphere for sustained release of nifedipine☆

Add time:08/30/2019    Source:sciencedirect.com

This article introduced the work of ethylcellulose based polymeric microsphere loaded with nifedipine for reduction in frequency of administration with low solubility in aqueous medium and high rate of absorption in the stomach. The non-aqueous polymeric suspension was put dropwise into an aqueous medium containing polyvinyl alcohol as a surfactant for the synthesis of microsphere by solvent evaporation. The microspheres were characterized by different techniques, namely, XRD, SEM, and NMR. The formation of microspheres was confirmed by SEM. XRD analysis revealed the semi-crystallinity nature of microspheres. The NMR study indicated the presence of hetero-aromatic nucleus in the microsphere.

We also recommend Trading Suppliers and Manufacturers of nifedipine iMpurity C (cas 111304-31-5). Pls Click Website Link as below: cas 111304-31-5 suppliers

Prev:Preparation of nano-alkalinecellulose carboxylates (NACCs) as the methylene blue sorbent and as the catalyst for the large-scale nifedipine synthesis
Next:Ultrasonication-assisted synthesis of sphere-like strontium cerate nanoparticles (SrCeO3 NPs) for the selective electrochemical detection of calcium channel antagonists nifedipine)