Nojirimycin and D-Glucono-1,5-lactone (cas 1335-57-5) as inhibitors of carbohydrases
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Add time:09/04/2019 Source:sciencedirect.com
Nojirimycin and D-Glucono-1,5-lactone (cas 1335-57-5) are powerful inhibitors of glucosidases, but poor inhibitors of exo-glucanases, endo-glucanases, and related enzymes. Nojirimycin can be used to differentiate between α-glucosidase and exo-α-d-glucanase, and between β-glucosidase and exo-β-d-glucanase. The structural similarity of the two inhibitors is discussed in relation to the mechanism of action of the enzyme types. Some data on d-glucal are included.
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