Effect of sugarcane molasses extract on the formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in a model system

Add time:07/16/2019    Source:sciencedirect.com

Molasses, the main by-product of sugar production, is a well-known source of antioxidants. In this study, sugarcane molasses extract was investigated for its total phenolic content and in vitro antioxidant capacity. The experimental total phenolic content was 101.3 mg of gallic acid equivalent (GAE) in 1 g of extract, IC50 of Trolox and sugarcane molasses extract were 125.33 μg/ml and 126.0 μg/ml, respectively. A chemical model system showed that the sugarcane molasses extract effectively reduced the formation of phenylacetaldehyde and the aldol condensation product, meanwhile, the amount of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) also decreased. This could be due to the reaction between the phenolic compounds of sugarcane molasses extract and the carbonyl group of phenylacetaldehyde inhibiting the aldol condensation product formation, and this would suppress the formation of PhIP. A pathway that phenolic compounds inhibited the formation of PhIP is proposed. This pathway also suggested a mechanism for how the sugarcane affects the formation of PHIP.

We also recommend Trading Suppliers and Manufacturers of 2-(1-Phenylethenyl)pyridine (cas 15260-65-8). Pls Click Website Link as below: cas 15260-65-8 suppliers

Prev:Effects of some cations on the formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in a model system
Next:Solubility of ionization behavior of the antifungal α-( 2,4-Difluorophenyl) -α-[(1-(2-(2-pyridyl)phenylethenyl)]-1H-1, 2,4-triazole-1-ethanol bismesylate (XD405))