Synthetic studies of carzinophilin (cas 1403-28-7). Part 4: Chemical and biological properties of carzinophilin (cas 1403-28-7) analogues☆
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Add time:09/01/2019 Source:sciencedirect.com
Chemical and biological properties of carzinophilin (cas 1403-28-7) congeners obtained in the course of our synthetic studies were investigated. These studies revealed feasibility for the use of some analogues as a double alkylating agent. Further, analogues carrying the naphthalene and the epoxide parts were found to show remarkable in vitro cytotoxicity and in vivo antitumor activity.
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