butriptyline (cas 15686-37-0): Improved gas-liquid chromatographic method using a nitrogen-phosphorus detector for its determination in serum

Add time:09/02/2019    Source:sciencedirect.com

We report a sensitive and specific method for the determination of butriptyline concentrations in serum by gas-liquid chromatography with a nitrogen phosphorus detector. The detection limit is 2 ng/ml, based on 3 ml of serum or plasma. The method has been validated in human volunteers receiving a single oral dose of 75 mg butriptyline hydrochloride.

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