Design, synthesis and antimycobacterial activity of 3,5-Dinitrobenzamide (cas 121-81-3) derivatives containing fused ring moieties
-
Add time:09/04/2019 Source:sciencedirect.com
We report herein the design, synthesis and antimycobacterial activity of 3,5-Dinitrobenzamide (cas 121-81-3) derivatives containing fused ring moieties. Results reveal that many of the target compounds have considerable in vitro antitubercular activity. Especially, N-((2-(4-fluorophenyl)/N-((2-(3-fluorobenzyl)-1,2,3,4-tetrahydroisoquilin-6-yl)methyl)-3,5-dinitrobenzamides 18a and 20e exhibit potent MIC values of 0.056–0.078 μg/mL against both drug-sensitive Mycobacterium tuberculosis (MTB) H37Rv strain and two clinically isolated multidrug-resistant MTB (MDR-MTB) strains, opening a new direction for further SAR studies.
We also recommend Trading Suppliers and Manufacturers of 3,5-Dinitrobenzamide (cas 121-81-3). Pls Click Website Link as below: cas 121-81-3 suppliers
Prev:Application of Propyl gallate (cas 121-79-9) alleviates pericarp browning in harvested longan fruit by modulating metabolisms of respiration and energy
Next:Synthesis and analysis of some adducts of 3,5-Dinitrobenzamide (cas 121-81-3)) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Square wave voltammetric determination of captopril in liquid phase using N-(4-hydroxyphenyl)-3,5-Dinitrobenzamide (cas 121-81-3) modified ZnO/CNT carbon paste electrode as a novel electrochemical sensor09/24/2019
- A high sensitive biosensor based on FePt/CNTs nanocomposite/N-(4-hydroxyphenyl)-3,5-Dinitrobenzamide (cas 121-81-3) modified carbon paste electrode for simultaneous determination of glutathione and piroxicam09/10/2019
- Identification of the major urinary and fecal metabolites of 3,5-Dinitrobenzamide (cas 121-81-3) in chickens and rats09/09/2019
- Simultaneous determination of N-acetylcysteine and acetaminophen by voltammetric method using N-(3,4-dihydroxyphenethyl)-3,5-Dinitrobenzamide (cas 121-81-3) modified multiwall carbon nanotubes paste electrode09/08/2019
- A novel additive organic supramolecular assembly: molecular complex of 3,5-Dinitrobenzamide (cas 121-81-3) and 3,5-dinitrobenzonitrile09/07/2019
- Concentration dependent colour switching of tryptophan-derived 3,5-Dinitrobenzamide (cas 121-81-3) ligands in the presence of fluoride anions09/06/2019
- Synthesis and analysis of some adducts of 3,5-Dinitrobenzamide (cas 121-81-3)09/05/2019
