Influence of the absolute configuration at C-4 in the binding of d-myoinositol 1,4,5 trisphosphate analogues to IP3 receptor
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Add time:09/08/2019 Source:sciencedirect.com
Biomimetic syntheses of enantiomerically pure 3-deoxy-d-muco- and d-myo-inositol-1,4,5 trisphosphate from d-glucose are described. Preliminary biological studies show a dramatic influence of the stereochemistry at C-4 on the binding to IP3 receptor.
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