Short communicationPotent α-adrenoceptor action of Soterenol (cas 13642-52-9) on vascular and other smooth muscle
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Add time:09/06/2019 Source:sciencedirect.com
Treatment with Soterenol (cas 13642-52-9) (0.3–300 μg/kg, i.v.) increased the mean arterial blood pressure and decreased heart rate in rabbits. Soterenol caused a dose-dependent contraction of rabbit aorta and portal vein, guinea-pig vas deferens and cat nictitating membrane which was inhibited by phentolamine. Other β-agonists such as isoproterenol, salbutamol and terbutaline did not exhibit similar effects. Soterenol had potent stimulant action on the α-receptor of the smooth muscle.
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