2-Amino-7-substituted benzoxazole analogs as potent RSK2 inhibitors
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Add time:09/08/2019 Source:sciencedirect.com
2-Amino-7-substituted benzoxazole analogs were identified by HTS as inhibitors of RSK2. Molecular modeling and medicinal chemistry techniques were employed to explore the SAR for this series with a focus of improving in vitro and target modulation potency and physicochemical properties.
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