Short communicationAntiviral evaluation of N-amino-1,2,3-triazoles against Cantagalo virus replication in cell culture

Add time:09/24/2019    Source:sciencedirect.com

This paper describes the antiviral evaluation of new N-amino-1,2,3-triazole derivatives, 1-(substituted-phenylamino)-5-methyl-1H-[1,2,3]-triazole-4-carboxylic acid ethyl esters, 3 and 1-(4-substituted-phenylamino)-5-methyl-1H-[1,2,3]-triazole-4-carboxylic acid hydrazides, 4, on Cantagalo virus replication. 1-(4-Fluoro-phenylamino)-5-methyl-1H-[1,2,3]-triazole-4-carboxylic acid hydrazide, 4e, exhibited a significant antiviral effect. Characterization of all compounds was confirmed by IR, 1H and 13C spectroscopies and elemental analysis. In addition, molecular structure of 4e was also reported.

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