Factors influencing the formation of 2-hydroxy-6-naphthoic acid from carboxylation of naphthol

Add time:09/06/2019    Source:sciencedirect.com

The synthesis of 2-hydroxy-6-naphthoic acid (2,6-HNA) from carboxylation of alkali-naphthoxide was studied with varying alkali cation types and reaction conditions such as reactant concentration, reaction time, temperature, and pressure. The product selectivity was strongly affected by the types of alkali cation, reaction time, and temperature, while the product yield was governed by reaction pressure. The maximum HNA yield, 28.6%, was achieved with 2,6-HNA selectivity of 81.6% at 6 atm of CO2, 543 K, and 6 h of reaction. The addition of K2CO3 led to further increase in the productivity of 2,6-HNA via suppression of the decarboxylation of HNA.

We also recommend Trading Suppliers and Manufacturers of 6-Hydroxy-2-naphthoic acid (cas 16712-64-4). Pls Click Website Link as below: cas 16712-64-4 suppliers

Prev:Transfer of heterocyclic carbene ligands from chromium to gold, palladium and platinum
Next:Thomasidioic acid and 6-hydroxy-5,7-dimethoxy-2-naphthoic acid: Are they really natural products?)