Diels-alder reactions of 1,2,4-triazines with cyclic vinyl ethers
-
Add time:09/10/2019 Source:sciencedirect.com
The Diels-Alder reaction of 1,2,4-triazines with cyclic vinyl ethers leads to a range of substituted pyridines with hydroxyalkyl and oxoalkyl side chains. With dihydrofuran the aromatization of the 1:1 adduct is inhibited by conformational factors and this allows 2:1 adducts to be isolated. Different regioselectivity is observed in the 2:1 adducts formed from ethyl 5-phenyl-1,2,4-triazine-3-carboxylate 1f and from ethyl 5,6-diphenyl-1,2,4-triazine-3-carboxylate 1b. An X-ray crystal structure of the 2:1 adduct 5 formed from 2,3-dihydrofuran and 1b is reported.
We also recommend Trading Suppliers and Manufacturers of METHYL 1,2,4-TRIAZINE-3-CARBOXYLATE (cas 16721-40-7). Pls Click Website Link as below: cas 16721-40-7 suppliers
Prev:A ready one-pot preparation for pyrrolo[2,1-f]-[1,2,4]triazine and pyrazolo[5,1-c]pyrimido[4,5-e]-[1,2,4]triazine derivatives
Next:Synthesis of isoquinolines by cycloaddition of arynes to 1,2,4-triazines) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Metalated azolo[1,2,4]triazines. II. Generation, C(4)-substituent dependent stability and electrophile trapping of 7-lithiopyrazolo[5,1-c][1,2,4]triazines09/26/2019
- Synthesis of 2-perfluoroalkyl-1,4-dihydropyrazolo[1,5-a][1,3,5]triazines via rearrangements of (1-perfluoroacetyl-1,4-dihydropyrazolo[5,1-c][1,2,4]triazin-4-yl)lithiums09/25/2019
- Synthesis of isoquinolines by cycloaddition of arynes to 1,2,4-triazines09/24/2019
- A ready one-pot preparation for pyrrolo[2,1-f]-[1,2,4]triazine and pyrazolo[5,1-c]pyrimido[4,5-e]-[1,2,4]triazine derivatives09/09/2019
- CuCl2 induced reactions of 6-ethynyl- and 6-cyano-5-aryl-2,2′-bipyridines with various N- and O-nucleophiles in comparison with the reactions of relative 1,2,4-triazines09/08/2019
- An unexpected synthesis of 3,5-diaryl-1,2,4-thiadiazoles from thiobenzamides and methyl bromocyanoacetate09/07/2019
- Synthesis of carbon-11-labeled 4-(phenylamino)-pyrrolo[2,1-f][1,2,4]triazine derivatives as new potential PET tracers for imaging of p38α mitogen-activated protein kinase09/06/2019
-
Health and Chemical more >
-
Related Products
- Methyl 1-Benzyl-5-oxopyrrolidine-3-carboxylate
- Methyl (((methoxymethylphosphinothioyl)thio)acetyl)methylcarbamate
- Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate
- Methyl (2-amino-5-methyl-1,3-thiazol-4-yl)acetate
- Methyl (2-chloromethyl)oxazole-4-carboxylate
- Methyl (2E)-3-(4-methylphenyl)propenoate
- Methyl (2E)-3-cyclohexylprop-2-enoate
- Methyl (2R)-2-[(tert-butoxycarbonyl)amino]-3-iodopropanoate
- Methyl (2R)-2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate
- Methyl (2R)-2-amino-2-cyclohexylethanoate hydrochloride