Muchimangins A–D: novel diphenylmethyl-substituted xanthones from Securidaca longepedunculata
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Add time:09/27/2019 Source:sciencedirect.com
Four new highly oxygenated xanthones, named muchimangins A–D (1–4), with a diphenylmethyl substituent have been isolated as extremely minor constituents from the root of Securidaca longepedunculata (Polygalaceae). Among them, muchimangin B (2) induced an apoptotic-like cell death of human pancreatic cancer PANC-1 cell line preferentially in nutrient deprived condition with PC50 of 38.9 μM.
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