PTSA–catalyzed functionalization of Hydroquinone (cas 123-31-9)s with benzhydryl alcohols in water
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Add time:09/26/2019 Source:sciencedirect.com
An intriguing and operationally simple direct benzylation of hydroquinones with benzhydryl alcohols has been developed using PTSA in water, affording functionalized hydroquinones in good to excellent yields. The advantages of being environmentally benign, metal-free, base-free, easy workup and having a wide substrate scope make it a promising process for the synthesis of symmetrically and unsymmetrically benzylated hydroquinones as well as for industrial applications.
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