A facile one-pot synthesis of 2-substituted-3-aminoquinolines: preparation of benzo[b]naphthyridine-3-carbonitriles

Add time:07/15/2019    Source:sciencedirect.com

A facile one-pot synthesis of 3-aminoquinolines from ortho-aminobenzaldehydes was developed. Ethyl 6,7-dimethoxy-3-aminoquinoline-2-carboxylate, a key intermediate for the preparation of a 4-anilino-benzo[b][1,5]-naphthyridine-3-carbonitrile, was efficiently prepared by this method. Synthetic routes to 4-anilino-benzo[b][1,5]-naphthyridine-3-carbonitrile and 4-anilino-benzo[b][1,8]-naphthyridine-3-carbonitrile are described

We also recommend Trading Suppliers and Manufacturers of 2-CHLORO-6,7-DIMETHOXY-3-QUINOLINECARBONITRILE (cas 93299-56-0). Pls Click Website Link as below: cas 93299-56-0 suppliers

Prev:Cyclization reactions of N-acryloyl-2-aminobenzaldehyde derivatives: formal total synthesis of martinellic acid
Next:Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts)