Phosphine-catalyzed [4+2] cycloaddition of sulfamate-derived cyclic imines with allenoates: synthesis of sulfamate-fused tetrahydropyridines

Add time:09/28/2019    Source:sciencedirect.com

Using n-PrPPh2 as the nucleophilic catalyst, the [4+2] cycloaddition reaction of the sulfamate-derived cyclic imines with allenoates works efficiently to yield various sulfamate-fused tetrahydropyridines in high yields with excellent diastereoselectivities. Using amino acid-based bifunctional phosphine as chiral catalyst, an asymmetric [4+2] cycloaddition reaction was achieved, giving chiral sulfamate-fused tetrahydropyridines in high yields with good enantiomeric excesses.

We also recommend Trading Suppliers and Manufacturers of Phenyl sulfamate (cas 19792-91-7). Pls Click Website Link as below: cas 19792-91-7 suppliers

Prev:Short communicationDiscovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors
Next:Human nutritional supplements in the horse: comparative effects of 19-norandrostenedione and 19-Norandrostenediol (cas 19793-20-5) on the 19-norsteroid profile and consequences for doping control)