Binding of methoxy-substituted N1-benzenesulfonylindole analogs at human 5-HT6 serotonin receptors

Add time:09/08/2019    Source:sciencedirect.com

Comparison of several amine-substituted and methoxy-substituted analogs of N1-(4-aminobenzene)sulfonylindole suggests that these substituents might contribute to the 5-HT6 serotonin receptor affinity of these agents via their electronic effect on the indolic nucleus. Their 1,2,3,4-tetrahydrocarbazole counterparts behave differently.

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