Efficient one-pot synthesis of β-phosphono malonates and 2-amino-4H-chromen-4-ylphosphonate derivatives by ethylenediamine diacetate-catalyzed three-component reactions

Add time:09/10/2019    Source:sciencedirect.com

One-pot three-component reactions of arylaldehyde or salicylaldehyde with malononitrile (or ethylcyanoacetate) and triethyl phosphite are carried out in the presence of ethylenediamine diacetate (EDDA) as a catalyst for the synthesis of biologically interesting β-phosphono malonates and 2-amino-4H-chromen-4-ylphosphonate derivatives. The value of this method lies in its mild reaction catalyst and conditions, good yields, and ease of handling.

We also recommend Trading Suppliers and Manufacturers of DIPROPYL MALONATE (cas 1117-19-7). Pls Click Website Link as below: cas 1117-19-7 suppliers

Prev:Highly efficient selective monohydrolysis of dialkyl malonates and their derivatives
Next:Influence of basicity on 1,3-butadiene formation from catalytic 2,3-butanediol dehydration over γ-alumina)