Cyclobutyl neighboring group effect on the stability of bicyclo-[2.2.2]octyl bridgehead carbenium ions☆
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Add time:09/26/2019 Source:sciencedirect.com
Solvolysis of the novel bridgehead cyclobutyl methyl chloride proceeds without skeletal rearrangement. Its relative rate is the first unequivocal proof for a small, but significant ability of the cyclobutyl group to stabilize an adjacent positively charged center.
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