Cu(II)-catalyzed one-pot synthesis of fully substituted dihydrothiophenes and thiophenes from thioamides and enynones
-
Add time:10/01/2019 Source:sciencedirect.com
A facile and direct synthetic method was developed for the construction of fully substituted dihydrothiophenes, which via a copper-catalyzed Michael addition/intramolecular cyclization/protonation cascade reaction of readily available thioamides with enynones under air atmosphere. This approach provides 2,3-dihydrothiophenes with up to 92% yield in a one-pot process. In addition, several fully substituted thiophenes could also be synthesized by changing the substituents of thioamides.
We also recommend Trading Suppliers and Manufacturers of 2,3-Dihydrothiophene (cas 1120-59-8). Pls Click Website Link as below: cas 1120-59-8 suppliers
Prev:Reactions of polyfluorinated thietanes: Selective synthesis of 4-R-2,2-bis(trifluoromethyl)thietane-1-S-oxides and 2-substituted 5-fluoro-4-(trifluoromethyl)-2,3-Dihydrothiophene (cas 1120-59-8)s
Next:Synthesis of 4-carboxy-2-thiabicyclo [3.2.0] Heptan-6-ones via 3-carboxy-2,3-Dihydrothiophene (cas 1120-59-8)s: potential β-lactamase inhibitors) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- A novel base-induced cyclization of selected benzyl alkynyl sulfides for the synthesis of 2-aryl-2,3-Dihydrothiophene (cas 1120-59-8)s09/30/2019
- Onion essential oil chemistry. Cis-and trans-2-mercapto-3,4-dimethyl 2,3-Dihydrothiophene (cas 1120-59-8) from pyrolysis of bis(1-propenyl) disulfide☆09/29/2019
- Synthesis of 4-carboxy-2-thiabicyclo [3.2.0] Heptan-6-ones via 3-carboxy-2,3-Dihydrothiophene (cas 1120-59-8)s: potential β-lactamase inhibitors09/28/2019
- Reactions of polyfluorinated thietanes: Selective synthesis of 4-R-2,2-bis(trifluoromethyl)thietane-1-S-oxides and 2-substituted 5-fluoro-4-(trifluoromethyl)-2,3-Dihydrothiophene (cas 1120-59-8)s09/27/2019
- 2,3-Dimethylene-2,3-Dihydrothiophene (cas 1120-59-8): The thiophene analogue of ortho-xylylene09/26/2019
- Thiophene, 2,3- and 2,5-dihydrothiophene, and tetrahydrothiophene hydrodesulfurization on Mo and Reγ-Al2O3 catalysts09/25/2019
- Formation amd reactions of 2,3-dimethylene-2,3-Dihydrothiophene (cas 1120-59-8)09/24/2019
- Copper-catalyzed tandem S-alkylation and S-alkenylation of sodium sulfide: synthesis of 2,3-Dihydrothiophene (cas 1120-59-8)s and thiophenes09/10/2019
- Synthesis of spirooxindoles bearing 2,3-(or 2,5-)dihydrothiophene-2-thione moiety via [3+2] annulation of carbon disulfide with Morita-Baylis-Hillman carbonates of isatins09/09/2019
