Pharmaceutical AnalysisAssay of Sulfacetamide sodium (cas 127-56-0) Ophthalmic Solutions by High‐pressure Liquid Chromatography

Add time:09/27/2019    Source:sciencedirect.com

A high‐pressure liquid chromatographic method, using an adsorption column and sulfabenzamide as the internal standard, is proposed for the determination of Sulfacetamide sodium (cas 127-56-0) and its principal hydrolysis product, sulfanilamide, in eye drops. It affords an average recovery of 100.9% of added sodium sulfacetamide with a relative standard deviation of 1.9%.

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