Short notePhotoinduced synthesis of quinoline derivatives catalyzed by organic photocatalyst at room temperature

Add time:09/24/2019    Source:sciencedirect.com

We describe 10-methyl-9,10-dihydroacridine (AcrH2), as an efficient metal-free photoredox catalyst for the synthesis of quinoline derivatives in a cascade annulation reaction. This new approach to construct multiply disubstituted quinoline derivatives is promoted by UV light. Various quinolines and tetrahydroquinolines are accessible at room temperature by single-electron transfer and intramolecular cyclization.

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