An unexpected ring-opening in the reissert reaction on 2,3-DIPHENYLQUINOXALINE (cas 1684-14-6)-n-oxide.

Add time:09/29/2019    Source:sciencedirect.com

When quinoxaline-N-oxide 1 is reacted with KCN and benzoyl chloride in water (the Reissert reaction) or methanol, the products are 2-,5- and 6- chloroquinoxaline (the latter being the major product: 42±6 %) and small amounts of 2-cyanoquinoxaline. Using three equivalents of trimethylsilyl cyanide instead of KCN, and dichloromethane as the solvent, leads to a 72 % yield of 2-cyanoquinoxaline. The reaction of trimethylsilyl cyanide and benzoyl chloride with 2,3-diphenylquinoxaline-N-oxide 2 leads to an unexpected ring-opening product 13; its structure is based on spectroscopic data and on an X-ray crystallographic analysis.

We also recommend Trading Suppliers and Manufacturers of 2,3-DIPHENYLQUINOXALINE (cas 1684-14-6). Pls Click Website Link as below: cas 1684-14-6 suppliers

Prev:Hypervalent iodine oxidation of benzil-α-arylimino oximes: an efficient synthesis of 2,3-DIPHENYLQUINOXALINE (cas 1684-14-6)-1-oxides
Next:Production of the potential sweetener 5-ketofructose (cas 1684-29-3) from fructose in fed-batch cultivation with Gluconobacter oxydans)