One-pot synthesis of symmetrical dinucleoside polyphosphates and analogs via 4,5-Dicyanoimidazole (cas 1122-28-7)-promoted tandem P–O coupling reactions
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Add time:09/27/2019 Source:sciencedirect.com
A novel one-pot protocol for the synthesis of symmetrical dinucleoside tri-, tetra-, and pentaphosphates, and their phosphonate analogs simply from nucleoside 5′-phosphoropiperidates has been developed by utilizing 4,5-dicyanoimidazole-promoted tandem P–O coupling reactions.
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