Chapter One - Recent advances in 1,2,4-triazolo[1,5-a]pyrimidine chemistry☆
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Add time:09/24/2019 Source:sciencedirect.com
The review deals with the pharmaceutically and agrochemically important group of 1,2,4-triazolo[1,5-a]pyrimidines (TPs) and covers relevant literature published from about 2006 through 2018. The synthetic section describes the formation of TPs from both aminotriazoles and pyrimidine derivatives by anellation of a second heterocyclic ring. In the structure-related section NMR spectra are stressed. Carbon–carbon coupling reactions and nucleophilic substitutions of functional groups provide the main focus of the reactivity-based section. Finally, progress in application is described.
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