The unimolecular dissociation of the glyoxylate, pyruvate, trifluoropyruvate, and α-oxobutyrate anions. Decarboxylation vs. decarbonylation of simple α-ketocarboxylates☆

Add time:09/28/2019    Source:sciencedirect.com

A series of simple α-oxo acids (RCOCOOH, R = H, CH3, CH3CH2, CF3) were deprotonated by negative electrospray ionisation and subjected to collision-induced dissociation and mass spectrometric analysis. Decarboxylation is the major process, observed for all four carboxylates. In addition, glyoxylate (R = H) and trifluoropyruvate (R = CF3) undergo efficient decarbonylation. Pyruvate (R = CH3) and 2-oxobutyrate (R = CH3CH2) also lose CO, but to a minor extent. The mechanistic and kinetic details of these processes have been investigated, supported by quantum chemical and RRKM modelling. The observed reactivity trends are in good agreement with conventional structure/reactivity relationships.

We also recommend Trading Suppliers and Manufacturers of Ethyl trifluoropyruvate (cas 13081-18-0). Pls Click Website Link as below: cas 13081-18-0 suppliers

Prev:Highly stereoselective trifluoropyruvate-ene reaction with Δ20(22)-steroidal olefin by chiral Pd2+-catalyst: New type of VDR antagonist for osteocalcin, Δ20(21)-ene product without (dehydro)lactone and lactam motifs
Next:Catalytic and highly enantioselective Friedel–Crafts type reactions of heteroaromatic compounds with trifluoropyruvate and glyoxylate by a dicationic palladium complex)