Copper-catalyzed decarboxylation/cycloaddition cascade of alkynyl carboxylic acids with azide

Add time:07/18/2019    Source:sciencedirect.com

A copper-catalyzed decarboxylation/cycloaddition cascade of alkynyl carboxylic acids with azide has been developed. This reaction exhibits good functional group tolerance and wide substrate scope, provides an efficient way to construct 1,4-disubstituted 1,2,3-triazoles.

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